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Prosys Isolators and Gloveboxes



Isolators

Prosys Isolator


MSE Data Sheet
Click here to download the Prosys Isolators Catalogue.

Laboratory and Analytical Isolators

  • Custom and standard isolators for analytical and QA laboratories.
  • Contained handling of samples for dispensing and analysis.
  • Integration of a wide range of different weigh scale systems and other instrumentation.
  • Provision of special atmospheres, such as inert, dry and gassed atmospheres.
  • Integration of work spaces, data hook up points and monitoring and recording instrumentation.
  • Integration with existing and new laboratory equipment.

Laboratory Small Scale Isolators

  • Custom gloveboxes to allow for contained small scale processing of HAPI compounds.
  • Gloveboxes may be linked directly to existing or new fume hoods via material transfer airlocks to segregate liquid processing within the fume hoods and solids handling within the glovebox.
  • Gloveboxes may contain a variety of different processing equipment, such as tray dryers, Nutsche filters, rotary evaporators, small scale reactors and crystallizers, etc.
  • Dispensing and packaging of final solids compound may be carried out within the Glovebox.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Dry Boxes

Dry Boxes

Dry Boxes

  • Dry chamber glovebox for analytical QA facility.
  • Achieves less than 1% RH by continuous Dew Point analysis.
  • Fully integrated recirculation desiccator system.
  • Nitrogen purge facility for airlock chamber and working chamber.
  • Air purge system to remove all nitrogen from either chamber before windows are unlocked for opening.
  • Full touch screen HMI that allows for monitoring the running and maintenance status of the isolator as well as fault diagnostics.
  • 'Traffic Light' type indicator to allow quick status check of isolator.
  • Integrated power sockets, service hook up points and data transfer points.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Encapsulators

Encapsulators and Tablet Press Isolators

Encapsulators and Tablet Press Isolators

  • High Containment Isolator retrofits to existing processing equipment (e.g. Encapsulators, Tablet Presses, etc.).
  • Fully contained powder infeed and final dosage form output.
  • Complete Project Management from Start to Finish, inclusive of any work being required from the OEM of the machine.
  • Integration and supply of ancillary equipment, like dust collectors, tablet samplers, de- dusters, metal checkers, solids feed systems, etc.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Sampling and Slurry Charging Gloveboxes

Sampling and Slurry Charging Gloveboxes

Sampling and Slurry Charging Gloveboxes

  • Multi-functional Glovebox system is integrated with the ProSys Recirculation Top Reactor Sampling System (RTRS).
  • Multi-function glovebox that can be mounted either for liquids/solids charging directly into the sight-glass assembly of the RTRS or for the contained removal of samples from the RTRS.
  • Transfer in/out of the glovebox via Rapid Transfer Port.
  • Working chamber is nitrogen purged.
  • Internal safe change HEPA filters (removal via Rapid Transfer Port).
  • Complete system can also be trolley mounted, when space on top of the reactor is limited.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Sterility Testing Isolators

Sterility Testing Isolators

Sterility Testing Isolators

  • Isolator for sterility testing: greatly reduces the risk of false positives.
  • Can be customised to fit customer application.
  • Can be fully bio-decontaminated using vaporised Hydrogen Peroxide. Integration with Steris or Bioquell gas generators.
  • Validated fast gassing cycle on airlock ports (single or multiple transfer ports possible).
  • h1O2 Cycle development and validation services offered.
  • Integrated pump for sterility testing, particle monitoring (viable and non viable), etc.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Large Scale Reactor Charging Gloveboxes

Large Scale Reactor Charging Gloveboxes

Large Scale Reactor Charging Gloveboxes



  • Large scale vessel charging glovebox from drums and other types of containers.
  • Drum interface with glovebox is via a host container to permit handling of differently sized drums without the need for changeover parts.
  • Material entry via Rapid Transfer Port, drum docking hoist or through opened front window.
  • Nitrogen purged working chambers with cascading pressure.
  • Twin Chamber design to protect the drum docking point from powder contamination.
  • Internal safe change inlet and outlet HEPA filters (changed via Rapid Transfer Port).
  • Single, double or triple chamber systems.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Mobile Seed Charging

Mobile Seed Charging Gloveboxes

Mobile Seed Charging Gloveboxes



  • Mobile slurry charging system for use with multiple process vessels.
  • 400mm height adjustability to provide optimum ergonomics for different height operators.
  • Solids enter the working chamber via Rapid Transfer Port.
  • Integrated pneumatic/magnetic stirrer for slurrying up of solids within the glovebox.
  • Pressure/vacuum transfer of slurry via disposable transfer lines.
  • Vacuum source, nitrogen purge for working chamber and slurrying bottle, low micron filtration of liquids and gasses are all integrated into the glovebox envelope.
  • Integrated flush/cleaning cycle for slurrying bottle and transfer lines.
  • Inlet and outlet HEPA filters are internal safe change (removal from glovebox via Rapid Transfer Port).

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Dispensing and Subdivision

Dispensing and Subdivision Gloveboxes

Dispensing and Subdivision Gloveboxes

  • Pharmaceutical active ingredients dispensing stations.
  • Designed to achieve an OEL of less than 1microgr/m3.
  • Fully automated nitrogen purge system and pressure control circuit.
  • Designed to dispense either into ILC Dover continuous liner or into Split Butterfly Valve (integrated into the base of the glovebox).
  • Drum docking to the base of the glovebox for either the removal or addition of small quantities.
  • Integrated weighscales.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Reactor Charging

Reactor Charging/Seeding Isolators

Reactor Charging/Seeding Isolators

  • Small scale vessel charging glovebox, e.g. Seed Charging, small liquid editions, etc.
  • Material entry via Rapid Transfer Port, Airlock (Passbox) or through opened front window.
  • Nitrogen purged working chamber.
  • Material transfer via funnel allows for cleandown of the glovebox without draining into the process vessel.
  • Internal safe change inlet and outlet HEPA filters (change via Rapid Transfer Port, Continuous Liner Port or Airlock).
  • Large radius corners and edges for ease of cleaning.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Vessel Top Sampling

Vessel Top Sampling Gloveboxes

Vessel Top Sampling Gloveboxes

  • Fully contained top vessel sampling station (solids and liquid sampling from reactors, dryers, etc.) Automated sample lance with removable and interchangeable sample cup arrangement Option for taking a fixed sample volume at a fixed level within the vessel.
  • Nitrogen purged glovebox chamber.
  • Sample transfer either via continuous liner system or via Rapid Transfer Port.
  • The top sampler principle has also been combined with pressure and vacuum rated cabinets and simple (non-glovebox) cabinets for non-toxic applications.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Filter Dryer Heel Removal

Dry Boxes

Filter Dryer Heel Removal and Discharge Gloveboxes

  • Isolators for sampling, solids discharge and heel removal from Nutsche filters, dryers and filter dryers or a combination of all these functions into one system.
  • Isolators are purpose built to suit existing and new filtration & drying equipment.
  • Existing filter dryer discharge valves are replaced with integrated solids discharge doors to allow for contained access to the filter dryer interior via the glovebox system.
  • Assessment of existing filtration & drying equipment for suitability for containment carried out by ProSys experts.
  • Drum filling may be via continuous liner system, split butterfly valve, ILC Dover type bags or inflatable seal head interface.
  • Integration of special atmospheres, solids metering, weighing, particle size reduction (screening, milling, etc.) and more into the containment system is possible.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Solids Drum Filling

Solids Drum Filling Systems

Solids Drum Filling Systems

  • Unloading of solids vessel to very low OEL's and high weighing accuracy.
  • Multiple filling heads for off- loading into either single liners via inflatable sealhead, continuous liner or RTP Managed airflow throughout the system to prevent cross contamination between chambers or fully segregated chambers Options for manual or fully integraded solids dosing system to achieve very high filling accuracies.
  • Solids chute nitrogen purge and filtered extract options Integrated weigh system and roller track.
  • Optional pneumatic drum pusher to assist in removal of filled product drums.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



Liquid Drum Unloading

Liquid Drum Unloading and Sampling Gloveboxes

Liquid Drum Unloading and Sampling Gloveboxes



  • Liquid drum unloading and sampling of toxic compounds.
  • Single chamber or multi chamber systems.
  • Small liquids additions or charges from large IBC’s.
  • Simple manual dip pipes or fully automated, fully sealed dip pipes with integrated nitrogen blanketing and WIP, blow down and drying cycles Drum weigh systems and automated dosing of the liquid transfer.
  • Hastelloy product contact surfaces for highly corrosive liquids (e.g. Bromine).

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.



In-line Filter Change

In-line Filter Change Gloveboxes

In-line Filter Change Gloveboxes

  • Contained systems for the safe removal of in-line cartridge filter elements.
  • Disposal of used filter cartridges via continuous linger system.
  • Nitrogen purge of working chamber.
  • Lift up windows for easy maintenance access to the filter housings.
  • Introduction of clean filter cartridges via airlock access.
  • Internal safe change HEPA filters (removal via continuous liner system).
  • Optional integrated storage racks.

Our years of experience ensures that we can help you select the best isolator or glovebox for your needs. Click HERE to arrange a consultation or request more information.

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